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Channel: Medical Xpress news tagged with:epigenetic mechanisms
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Lab-made tissue picks up the slack of Petri dishes in cancer research

New research demonstrates that previous models used to examine cancer may not be complex enough to accurately mimic the true cancer environment. Using oral cancer cells in a three-dimensional model of...

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Gene regulator in brain's executive hub tracked across lifespan

For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain's executive hub. Among key...

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Cell contents may be key to controlling toxicity of Huntington's disease protein

New research into the cell-damaging effects of Huntington's disease suggests a potentially new approach for identifying possible therapeutic targets for treating the nerve-destroying disorder.

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Replicating risk genes in bipolar disorder

One of the biggest challenges in psychiatric genetics has been to replicate findings across large studies.

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Colon cancer exhibits a corresponding epigenetic pattern in mice and humans

Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction...

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Life experiences put their stamp on the next generation: New insights from...

The 18th century natural philosopher Jean-Baptiste Lamarck proposed that the necks of giraffes lengthened as a consequence of the cumulative effort, across generations, to reach leaves just out of...

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Mechanisms regulating inflammation associated with type 2 diabetes, cancer...

A study led by researchers at Boston University School of Medicine (BUSM) has identified epigenetic mechanisms that connect a variety of diseases associated with inflammation. Utilizing molecular...

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Epigenetics mechanism may help explain effects of mom's nutrition on her...

Pioneering studies by U. S. Department of Agriculture-funded research molecular geneticist Robert A. Waterland are helping explain how the foods that soon-to-be-moms eat in the days and weeks around...

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KDM1 may represent a new therapeutic target for glioma

Researchers have generated preclinical data demonstrating that the protein KDM1, which functions as a lysine demethylase, is a potential target for glioma treatment, according to Gangadhara R. Sareddy,...

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The relationship between prenatal stress and obesity is confirmed in rats

The intrauterine environment plays an important role in the health of the offspring. Now, experts from the University of Navarra affirm that the mother's stress, due to socio-economic or psycho-social...

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Soy-based compound may reduce tumor cell proliferation in colorectal cancer

Research on a soy-based treatment for colorectal cancer, a promising agent in ovarian cancer, and a new drug target for advanced prostate cancer was presented at the American Association for Cancer...

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Researchers discover possible trigger for spread of head and neck cancer cells

(Medical Xpress)—Very little has been known about the epigenetic events—developmental and environmental factors affecting genes—that occur prior to the invasive growth of head and neck squamous cell...

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Fetal stress disrupts the way genes are transmitted

If you think stress is killing you, you may be right, but what you don't know is that stress might have harmed your health even before you were born. In a new report appearing in the August 2013 issue...

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BUSM researchers study epigenetic mechanisms of tumor metastasis for improved...

A review article by researchers at Boston University School of Medicine (BUSM) suggests that epigenetics may be a useful target to stop the growth, spread and relapse of cancer. The findings are...

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Helping good genes win in brain cancer cells

Researchers at the Federal University of Rio Grande do Sul (UFRGS) have shown that manipulating an epigenetic mechanism, which regulates gene expression, may promote cell death and favor maturation...

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Epigenetics: A new link between nutrition and cancer

In "Epigenetics: A New Link Between Nutrition and Cancer", a recent article from Nutrition and Cancer: An International Journal, a publication of Routledge, researchers explore the possible effects...

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Some breast cancer tumors hijack patient epigenetic machinery to evade drug...

A breast cancer therapy that blocks estrogen synthesis to activate cancer-killing genes sometimes loses its effectiveness because the cancer takes over epigenetic mechanisms, including permanent DNA...

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Drilling into the trends in genetics and epigenetics of aging and longevity

An international group of scientists performed a comprehensive analysis of the genetic and epigenetic mechanisms and demonstrated that the majority of the genes, as well as genetic and epigenetic...

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Not only in DNA's hands: Epigenetics has large say in blood formation

Blood stem cells have the potential to turn into any type of blood cell, whether it be the oxygen-carrying red blood cells, or the many types of white blood cells of the immune system that help fight...

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Researchers find why depression and aging linked to increased disease risk

Psychological stress and stress-related psychiatric disorders are associated with increased risk for aging-related diseases, but the molecular mechanisms underlying this relation are unknown....

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